Simultaneous Determination of Cinnarizine and Dimenhydrinate in Binary Mixture Using Chromatographic Methods
نویسندگان
چکیده
منابع مشابه
Development of normalized spectra manipulating spectrophotometric methods for simultaneous determination of Dimenhydrinate and Cinnarizine binary mixture.
Simultaneous determination of Dimenhydrinate (DIM) and Cinnarizine (CIN) binary mixture with simple procedures were applied. Three ratio manipulating spectrophotometric methods were proposed. Normalized spectrum was utilized as a divisor for simultaneous determination of both drugs with minimum manipulation steps. The proposed methods were simultaneous constant center (SCC), simultaneous deriva...
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Four simple, specific, accurate and precise spectrophotometric methods are developed and validated for simultaneous determination of cinnarizine (CIN) and dimenhydrinate (DIM) in a binary mixture with overlapping spectra, without preliminary separation. The first method is dual wavelength spectrophotometry (DW), the second is a ratio difference spectrophotometric one (RD) which measures the dif...
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Determination of Amlodipine and Valsartan in Binary Mixture Using Derivative- Ratio Spectrophotometric, Chemometric and High Performance Liquid Chromatographic-UV Methods
Three methods were developed for simultaneous determination of amlodipine and valsartan without previous separation. The first method depends on first derivative of the ratios spectra (DD1) by measurements of the amplitudes at 234.5 and 247 nm for amlodipine using 30μg/mL of valsartan as a divisor and at 282 and 292 nm for valsartan using 80μg/mL of amlodipine as a divisor. Calibration graphs w...
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ژورنال
عنوان ژورنال: Journal of Chromatographic Science
سال: 2015
ISSN: 0021-9665,1945-239X
DOI: 10.1093/chromsci/bmv103